منابع مشابه
Pancreatic polypeptide.
Pancreatic polypeptide (PP) was discovered fortuitously during the purification of insulin from birds (Kimmel et al., 1968) and later from mammals (Chance et al., 1976). PP has since been extracted and purified from several mammalian species. It contains 36 amino-acid residues and is quite distinct from other known hormonal peptides (Lin and Chance, 1974). The amino-acid sequence of the peptide...
متن کاملPancreatic Polypeptide
Pancreatic Polypeptide (PP) is a 36 amino acid peptide produced and secreted by PP cells (originally termed F cells) of the pancreas which are primarily located in the Islets of Langerhans. It is part of a family of peptides that also includes Peptide YY (PYY) and Neuropeptide Y (NPY). PP is rapidly released after a meal but remains elevated for 4-6 hours in humans with the Vagus nerve being th...
متن کاملA Pancreatic Polypeptide-Producing Pancreatic Tumor Causing WDHA Syndrome
We report the case of a 46-year-old female patient with WDHA (watery diarrhea/hypokalemia/achlorhydria) syndrome caused by a pancreatic polypeptide-producing tumor in the head of the pancreas. Whereas VIP and other pancreatic endocrine hormones were in the normal range, only serum levels of pancreatic polypeptide were elevated. Imaging studies identified a pancreatic tumor in the head of the gl...
متن کاملPancreatic polypeptide and exocrine pancreatic function in the elderly.
The relationship between exocrine pancreatic function and plasma pancreatic polypeptide levels was studied in 14 normal elderly subjects and in ten elderly patients with exocrine pancreatic insufficiency determined by the para-amino-benzoic acid test. There was a decrease in the total pancreatic polypeptide response after a standard mixed meal in the group with pancreatic insufficiency (t = 2.7...
متن کاملPharmacokinetics of pancreatic polypeptide in man.
Pure bovine pancreatic polypeptide (PP) was infused into 23 healthy subjects at doses of 1, 3, and 5 pmol/kg/min over 60 minutes and plasma PP was measured by radioimmunoassay. During the infusions mean plasma levels of 203 +/- 34, 575 +/- 73, and 930 +/- 48 pmol/l respectively were achieved. Mean disappearance half time on stopping the infusion was 6.9 +/- 0.3 min (mean +/- SEM). The metabolic...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1978
ISSN: 0021-9746
DOI: 10.1136/jcp.s1-8.1.43